Two kicker comp 10 subs with KAC-6202 amp (kenwood)?

As long as it is wired correctly and you don't try to kill it by turning the bass and loudness clear up yes it will work, however as a subwoofer application, its quite small 100 watts X2 at 4 ohm. Without knowing the model of you speakers, Kicker 10's can take around 400 watts rms so I would look for an amp around 700-800 watts rms and a mono block. I think that you would be much happier with the results.